I think this is a real thing, especially for people who dabble and do the same routine weekly with light to moderate weights (They think they are lifting heavy and really working)
I am one of those folk with everything but legs. I kill legs to the point I walk out of the gym like a newborn giraffe.
But I can tell when I switch it up and do new exercises and such with either lower reps and higher weights or even higher reps and lower weights I get better pumps and soreness.
I do switch up once a month my leg routine. Think that is good? Starting with squats makes since to me as I can lift more weight and get more sets in. But when I pre-fatigue them with leg extensions and leg curls or hack squats I seem to get just as sore oreven more so.