I had 3 done starting in November 2015 and got my 3rd 12 weeks later. Two herniated discs. First shot did nothing really. I was in absurd amounts of pain that I always wanted to throw up. I went to Mexico 4 days later on a planned vacation. I got around but it was painful. So I will say the first only took a slight edge off the misery I was in. next shot was 6 weeks later and again minor relief but better again. Another 6 weeks and 3rd shot was the trick, pain was gone and, knock wood, still doing well. Thankfully because they said limit was 3 shots during that time.