Important hgh users! (metacresol)
Important! HGH USERS (METACRESOL)
1. Why is Metacresol needed with multi vials HGH?
2. Answer: METACRESOL is used in pens and multi use vials. Once you move up to 150 ius Or more of HGH in a single use vial you need this preservative. This will prevent contamination and degradation. It will prevent destroying or degrading of your HGH. Legit manufactures will provide this information in insert instructions. BEWARE of anyone telling or offering 150 iu HGH or more and don’t either include or instruct you use water containing METACRESOL. Most pens already include METACRESOL or a phenolic. Depending on your country name may differ. The new Spectrum 150 iu HGH is a multi use vial. Go will need the
the bac water included and part sterile water See more information on METACRESOL and it’s use below.
The diluent contains bacteriostatic water for injection with 0.33% metacresol as a preservative is added.
Multi-dose protein formulations require an effective antimicrobial preservative (AP) to inhibit microbial growth during long-term storage of unused formulations.
After performing various tests we came to conclusion:
Preservatives, either singly or in synergistic combinations remain necessary to prevent microbial contamination of multi-use liquid or semi-solid medicinal products, particularly from opportunistic pathogens. Solutions containing antimicrobial preservatives were challenged with microorganisms, sampled from 0.5 to 6 h following introduction of the challenge, cultured, and counted for surviving microbial cells. Data were analyzed by computer according to two models: linear and quadratic. Decimal reduction times (D values) were calculated for each microbial challenge in each preservative solution. A D value of less than or equal to 2 h for bacteria predicts that the preservative system will pass the British Pharmacopoeia (BP) preservative efficacy test, a more rigorous test than the USP test. Fourteen preservative systems were tested in both neutral isotonic saline solutions and neutral regular insulin solutions. D values and correlation coefficients for both models were calculated. The ranking of preservative effectiveness in neutral saline solutions closely correlated with the results found using neutral regular solutions.
The most effective preservative systems were found to be 0.3% m-cresol and various combinations of m-cresol and phenol.
(KNOWLEDGE IS POWER)
EG
The diluent contains bacteriostatic water for injection with 0.33% metacresol as a preservative is added.
Multi-dose protein formulations require an effective antimicrobial preservative (AP) to inhibit microbial growth during long-term storage of unused formulations.
After performing various tests we came to conclusion:
Preservatives, either singly or in synergistic combinations remain necessary to prevent microbial contamination of multi-use liquid or semi-solid medicinal products, particularly from opportunistic pathogens. Solutions containing antimicrobial preservatives were challenged with microorganisms, sampled from 0.5 to 6 h following introduction of the challenge, cultured, and counted for surviving microbial cells. Data were analyzed by computer according to two models: linear and quadratic. Decimal reduction times (D values) were calculated for each microbial challenge in each preservative solution. A D value of less than or equal to 2 h for bacteria predicts that the preservative system will pass the British Pharmacopoeia (BP) preservative efficacy test, a more rigorous test than the USP test. Fourteen preservative systems were tested in both neutral isotonic saline solutions and neutral regular insulin solutions. D values and correlation coefficients for both models were calculated. The ranking of preservative effectiveness in neutral saline solutions closely correlated with the results found using neutral regular solutions.
The most effective preservative systems were found to be 0.3% m-cresol and various combinations of m-cresol and phenol.