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National Library of Medicine => National Library of Medicine => Topic started by: Big Chicken on November 09, 2022, 06:39:11 pm

Title: A Study of Effects of Growth Hormone and Oxandrolone and Linear Growth (TS)
Post by: Big Chicken on November 09, 2022, 06:39:11 pm
Effect of growth hormone and oxandrolone singly and together on growth rate in girls with X chromosome abnormalities
D Rudman, M Goldsmith, M Kutner, D Blackston
PMID: 7350294 DOI: 10.1016/s0022-3476(80)80349-0
Abstract
The linear growth effects of oxandrolone, human growth hormone, and Ox + hGH were compared in six girls, age 11 to 15 years, with X chromosome abnormalities (three with X,O karyotype, three with Turner syndrome variants). Over six successive three-month periods, the patient received either no treatment, Ox, hGH, or Ox + hGH. The data demonstrate a significant (P less than 0.001) synergistic effect between Ox and hGH in stimulating linear growth in Turner syndrome and its variants.