Coming soon to USA market
Testosterone undecanoate is a form of testosterone steroid containing a larger ester (undecanoate) than many other types. It is available in both oral and injectable forms, and there are different brand names for each.
Testosterone Undecanoate Cycle
Testosterone Undecanoate Cycle
The oral form of testosterone undecanoate is called Andriol, while the brand name of injectable Testosterone undecanoate is Nebido. Neither product is available in the USA as an approved drug on prescription, but they are prescribed in many other countries.
Testosterone undecanoate has been developed for medical use to treat low testosterone, but like other synthetic testosterone steroids it’s also very appealing to anabolic steroid users as it provides all the benefits you can expect from a testosterone steroid when used for performance enhancement or testosterone replacement purposes.
As you will see, Testosterone undecanoate is not likely to be the first choice of any bodybuilder or athlete looking to use a pure testosterone steroid, simply due to its large ester that results in a very slow release.
Although the hormone itself is exactly the same as we find in more commonly used testosterone compounds like Testosterone enanthate, the Testosterone undecanoate ester can make it difficult to gain benefits in a performance enhancement setting.
Author’s Note: The following guide is based on my personal experience and does NOT promote the illegal use of steroids (PEDs).
What is Testosterone Undecanoate?
This is a long acting, and slow release steroid that when used in injection form can last several months in the system.
Testosterone Undecanoate Structure
Testosterone Undecanoate Structure
Due to this slow activity, its positive benefits can be very delayed and may not even begin to be beneficial until near the end of a normal length steroid cycle. This makes Testosterone Undecanoate less practical for many users of performance enhancing steroids compared with other esters of testosterone.
Andriol (Oral)
There is only one capsule size available, which is 40mg. Although there is 40mg of the active ingredient testosterone undecanoate in each capsule, only about one quarter or less will be absorbed by the body due to the oral method resulting in low bioavailability of the active ingredient.
This is one reason some guys will prefer the injectable form. Like all testosterone steroids, Andriol can can used in both bulking and cutting cycles. Testosterone encourages the retention of muscle when cutting and eating less calories than usual to encourage fat loss.
One of the benefits of Andriol is that unlike many other oral steroids, this one is not toxic to the liver because it does not pass through the liver. While this is a benefit, for most users the downsides will outweigh the lack of liver toxicity and this includes the high cost of the product when considering the high dosages that will be needed to reap the most benefits.
Nebido (Injectable)
For performance enhancement purposes, users would need to include Testosterone Undecanoate in a cycle that’s a minimum of 16 weeks in length, otherwise this slow acting testosterone form will not have enough time to provide any benefit. For this reason, most bodybuilders and athletes will choose one of the faster acting esters of testosterone instead.
Nebido will provide all the same benefits and effects that you experience with any other testosterone steroid, but they will take much longer to start happening. Most bodybuilders want to start seeing results within the first few weeks of a cycle, and this is simply not possible when using Nebido as a main anabolic compound. Only in the most specialist of circumstances will Nebido be a suitable choice for a bulking or cutting cycle.
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Testosterone Undecanoate Benefits
Testosterone Undecanoate, in both oral and injection form, will deliver the same benefits and effects as all esters of testosterone. The testosterone hormone itself is unchanged, and retains its 100 anabolic and 100 androgenic rating.
This steroid can be used in two main ways:
as a testosterone replacement at a low dosage during a steroid cycle where you need an external testosterone source to maintain levels and function due to the hormone suppression caused by other compounds
Testosterone Undecanoate can itself be used as a performance enhancement compound at higher doses.
The effects that testosterone, when used at high performance enhancement doses, will have on the male body include:
Increased nitrogen retention – a positive nitrogen balance is critical for muscle growth. If the nitrogen balance falls into the negative, the body can enter a catabolic state instead of anabolic and muscle will be lost. Testosterone will boost nitrogen retention to a higher level than can be naturally achieved without the use of steroids.
Enhances protein synthesis – encourages the cells to make more proteins which fuel muscle growth. Regular resistance training and quality protein food intake also promote protein synthesis, and when combined with a testosterone steroid at high doses this process is significantly enhanced; forming the basis for the substantial muscle mass growth you can achieve when using Testosterone Undecanoate.
Increases IGF-1 production – this growth hormone is vital for its anabolic effects on skeletal muscle and in the production of more protein. IGF-I may also stimulate muscle satellite cells which is a process that’s needed to fuel an increase in muscle size.
Increases red blood cell count – more red blood cells transporting more oxygen carrying hemoglobin and nutrients to the muscles means better performance, improved endurance and enhanced recovery through the increased removal of acid from cells that oxygen is capable of.
Decreases levels of glucocorticoids – these stress hormones naturally increase when undertaking intense physical exercise and they contribute to a loss of muscle mass by causing a loss of protein and having a negative effect on insulin which is an important anabolic regulator. Testosterone can reduce levels of glucocorticoids so you can avoid this muscle wastage and remain anabolic.
If you are experienced using any other form of testosterone such as cypionate, enanthate, propionate or suspension, you will be familiar with all the benefits and effects of Testosterone Undecanoate as the hormone is unaltered.
Testosterone Undecanoate Dosage
Both forms of Testosterone Undecanoate present challenges when used in a performance enhancement steroid cycle. Most experienced and new steroid users will find Testosterone Undecanoate to be a much less practical and effective choice of compound compared with the much more commonly used esters of testosterone like enanthate.
While a great benefit of this slow acting injection form is how sparse your injections will be, this needs to be weighed up with how long you’ll be waiting to see any results.
Andriol (Oral) Dosage and Cycle Length
To get performance enhancement benefits from Andriol, you would need to use a very high dose of this oral steroid. This is quite an expensive steroid, and additionally there is no scientific information available about the health impacts of consuming such high doses over long periods of time. Up to 500mg daily would need to be taken of Andriol due to the low bioavailability of each 40mg capsule. The cycle length would need to be similar to a standard steroid cycle at 8 to 12 weeks long.
Nebido (Injectable) Dosage and Cycle Length
If you’re wanting to do a short steroid cycle, then Nebido won’t fit the bill for you because your cycle length with this compound will need to be at least 16 weeks because of how long this injected hormone takes to start having an effect. 8 or even 12 weeks just doesn’t give Nebido enough time to take full effect.
Dosage of Nebido will depend on what your purpose for using it is: as a testosterone support when using other compounds, 1000mg to last 12 weeks is suitable but again, because it is such a slow acting compound it will not provide the immediate relief to testosterone suppression that you’ll be needing so there is unlikely to be a scenario when it will be used in a performance enhancement setting for this purpose.
When using Nebido as a primary anabolic compound or alongside other steroids in a stack, the dosage of 1000mg can be more frequent; at least once per month or in some cases twice monthly. Most users will not benefit from a compound like Nebido that takes a considerable amount of time to kick in, and therefore you are likely to be selecting one of the much faster acting forms of testosterone.
Testosterone Undecanoate for TRT
When used medically for low testosterone treatment, Nebido is usually injected every 3 months at 1000mg. But again, due to the fact steroid users will be using other compounds that have a rapid effect on natural testosterone production, Nebido is too slow acting to be useful as a testosterone replacement during most steroid cycles.
While the oral Andriol is faster acting, daily doses of up to 160mg as a testosterone replacement can make this a very expensive option when compared to other testosterone compounds.
Andriol vs. Nebido
The only difference between these two forms of Testosterone Undecanoate are the method of administration; Andriol is an oral capsule, while Nebido is an injection. The testosterone hormone is exactly the same, with the same ester attached.
The difference occurs in the body thanks to the way each one is consumed and metabolized, with Andriol having a much shorter elimination half life and faster action, but needing to be administered often to keep blood levels an the optimal level.
Although each capsule of Andriol contains 40mg of testosterone, the majority of this is not taken up by the body; in fact less than 10% of the hormone is absorbed. This results in a significantly higher dosage being needed in order to meet your targeted dosage amount; making Andriol almost impossibly impractical and expensive to use for performance enhancement due to the significant amount of the steroid you would need to purchase and use.
In contrast, injecting Nebido puts you on a slow course to receive the full dosage of testosterone over a long period of time. Bodybuilders will need to wait a considerable time – measuring many weeks to months – to see results from Nebido. For that reason alone it is not often considered a steroid that is useful for most performance enhancement cycles.
https://www.drugs.com/cdi/testosterone-undecanoate-injection.html