The thing I have a hard time understanding when I hear people using anavar as TRT, is that it will eventually wreck your lipid profile. It is not a matter of if, but a matter of when. How long a person can run it, before it happens is individually dependent, but it is going to happen. I have read and heard this from multiple sources, including those who run blood clinics, anavar has a 30-50% greater impact on lipids than testosterone.