After each Inject. 7-10 after injection. You still have mg left in you from last injection. For TRT user after a month are so. Their labs have high readings of testosterone. This is when the Endo will tell you how much to cut back and if your Hemo ect is showing 52-54 and 18 on the other they will tell you how much to cut back. In order to lower blood thickness. Everyone is different. Weekly dose for you might not work for next mate.